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Cannabis and Psychosis: Challenging Misconceptions and Embracing Evidence



As public interest and scientific research surrounding cannabis continue to grow, it is essential to critically analyse and understand the findings within the context of a nuanced perspective. Recent studies have shed light on the relationship between cannabis use and various mental health outcomes, challenging long-held assumptions. In this article, we delve into the latest research, questioning the commonly propagated negative associations and advocating for a more balanced viewpoint on cannabis.



Dispelling the Myth of Cannabis Dependence:

A study publish recently, titled "High potency cannabis use, mental health symptoms and cannabis dependence: Triangulating the evidence" examined the association between THC concentration in cannabis and cannabis dependence. In a cross-sectional study of 410 participants donated a sample of cannabis for analysis of THC concentration and reported their cannabis potency preference. These two exposure measures were investigated for their association with cannabis dependence, depression, anxiety, and psychosis-like symptoms. Surprisingly, the findings revealed there was weak evidence of a small association between cannabis potency and depression and anxiety. There was no association between high potency cannabis preference or THC concentration in cannabis and psychosis-like symptoms. This study challenges the popular belief that higher potency cannabis inevitably leads to dependence. While further research is needed, these results encourage a reevaluation of the existing assumptions regarding cannabis addiction.



Unravelling the Complexities of Mental Health:

Another significant study examining the Influence of cannabis use on the incidence of psychosis in people at clinical high risk investigated the link between cannabis use and psychosis. The study examined 344 participants between 16-34 years old across Europe, Australia, and South America over 2 years. Contrary to conventional wisdom, the research found that there was no evidence that cannabis use in people at high risk of psychosis had a significant effect on the incidence of psychosis or other adverse clinal outcomes. This challenges the notion that cannabis is a direct cause of psychotic disorders and highlights the importance of examining other factors that contribute to mental health conditions.



Examining the Bidirectional Relationship:

The relationship between cannabis use and schizophrenia is a topic of ongoing debate. A comprehensive study examining the relationship between cannabis and schizophrenia found weak evidence supporting a link from initial cannabis use to schizophrenia. However, it found much stronger evidence for a causal link from schizophrenia to cannabis use. This suggests that individuals with schizophrenia may have a higher risk of initiating cannabis use. Therefore, it is crucial to recognise that the relationship between cannabis and schizophrenia is complex and multifaceted, requiring further exploration.



Advocating for Informed Cannabis Policies:

The emerging evidence challenging the negative associations between cannabis use and mental health outcomes highlights the need for informed and evidence-based cannabis policies. Rather than succumbing to sensationalism and fearmongering, it is imperative to consider the broader context of individual vulnerabilities, genetic predispositions, and environmental factors that contribute to mental health conditions.


The current body of research presents a compelling case for challenging conventional assumptions surrounding cannabis. The studies discussed above provide evidence against the commonly held beliefs regarding cannabis dependence, psychosis, and schizophrenia. Our drug policies should embrace evidence-based findings, encourage responsible use, and advance our understanding of this complex plant. By fostering a more balanced and informed perspective, we can make meaningful progress in shaping cannabis policies and promoting the well-being of individuals who choose to use cannabis.

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